Crystallography grade
CLEC4A
Spezies: Human
Wirt: Insektenzellen
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, ELISA, SDS, Crys
CLEC4A
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Lagerung
-20 °C,-80 °C
Informationen zur Lagerung
-20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Haltbarkeit
12 months
Target
CLEC4A
(C-Type Lectin Domain Family 4, Member A (CLEC4A))
CLEC4A Protein, CLECSF6 Protein, DCIR Protein, DDB27 Protein, LLIR Protein, Clecsf6 Protein, Dcir1 Protein, Clec4a Protein, zinc finger protein 705A Protein, C-type lectin domain family 4 member A Protein, C-type lectin domain family 4, member A Protein, C-type lectin domain family 4, member a2 Protein, ZNF705A Protein, CLEC4A Protein, Clec4a Protein, Clec4a2 Protein
Hintergrund
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.
Molekulargewicht
46.3 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.