CTGF Protein (AA 27-349) (His tag)

Produktnummer ABIN7274340

Produktdetails

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-349

Spezies: Rhesusaffen

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CTGF Protein ist gelabelt mit His tag.

Verwendungszweck: Rhesus macaque CTGF/CCN2 Protein

Sequenz: Gln27-Ala349

Produktmerkmale: Recombinant Rhesus macaque CTGF/CCN2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln27-Ala349.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Rhesus macaque CTGF, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CTGF Antibody, hFc Tag with the EC50 of 8.7ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS, 0.2M Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Andere Bezeichnung: CTGF (CTGF Produkte)

Synonyme: Ccn2 Protein, Fisp12 Protein, Hcs24 Protein, fisp-12 Protein, CCN2 Protein, HCS24 Protein, IGFBP8 Protein, NOV2 Protein, CTGRP Protein, ctgf Protein, hm:zeh1559 Protein, si:dkey-266k12.4 Protein, wu:fl25c03 Protein, zeh1559 Protein, zgc:136644 Protein, XCTGF Protein, ccn2 Protein, nov2 Protein, hcs24 Protein, igfbp8 Protein, CTGF Protein, si:ch211-173b8.2 Protein, connective tissue growth factor Protein, connective tissue growth factor a Protein, connective tissue growth factor L homeolog Protein, connective tissue growth factor b Protein, Ctgf Protein, CTGF Protein, ctgfa Protein, ctgf.L Protein, ctgf Protein, ctgfb Protein

Hintergrund: Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.

Molekulargewicht: 36.52 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

UniProt: H9FQD5

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding