CEACAM8 Protein (AA 35-319) (His tag)

Produktnummer ABIN7274330

Produktdetails

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Protein-Typ: Recombinant

Proteineigenschaft: AA 35-319

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CEACAM8 Protein ist gelabelt mit His tag.

Verwendungszweck: Human CEACAM-8/CD66b Protein

Sequenz: Gln35-Ser319

Produktmerkmale: Recombinant Human CEACAM-8/CD66b Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln35-Ser319.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 4.59 μM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CEACAM8 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8))

Andere Bezeichnung: CEACAM-8 (CEACAM8 Produkte)

Synonyme: CD67 Protein, CGM6 Protein, CD66b Protein, NCA-95 Protein, CEACAM8 Protein, CEACAM1 Protein, MGC142545 Protein, cd67 Protein, cgm6 Protein, cd66b Protein, nca-95 Protein, carcinoembryonic antigen related cell adhesion molecule 8 Protein, carcinoembryonic antigen related cell adhesion molecule 1 Protein, carcinoembryonic antigen-related cell adhesion molecule 8 Protein, CEACAM8 Protein, CEACAM1 Protein, LOC612469 Protein, ceacam8 Protein

Hintergrund: Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes.

Molekulargewicht: 32.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_001807