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CD1a Protein (CD1a) (AA 19-300) (His tag)

CD1a Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274279
  • Target Alle CD1a Proteine anzeigen
    CD1a
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 19-300
    Spezies
    • 8
    • 1
    Human
    Quelle
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD1a Protein ist gelabelt mit His tag.
    Verwendungszweck
    Human CD1A Protein
    Sequenz
    Asp19-Val300
    Produktmerkmale
    Recombinant Human CD1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp19-Val300.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CD1a
    Andere Bezeichnung
    CD1A (CD1a Produkte)
    Synonyme
    CD1 Protein, FCB6 Protein, HTA1 Protein, R4 Protein, T6 Protein, CD1A Protein, CD1a molecule Protein, CD1 antigen Protein, T-cell surface glycoprotein CD1a Protein, CD1A Protein, CD1.1 Protein, LOC100156095 Protein, LOC101111409 Protein
    Hintergrund
    CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms.
    Molekulargewicht
    33.3 kDa. Due to glycosylation, the protein migrates to 48-53 kDa and 13-14 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    NP_001754
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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