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CD37 Protein (AA 113-240) (Fc Tag)

TSPAN26 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274150
  • Target Alle CD37 (TSPAN26) Proteine anzeigen
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 113-240
    Spezies
    • 9
    • 2
    Human
    Quelle
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD37 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Human CD37 Protein
    Sequenz
    Ala113-Asn240
    Produktmerkmale
    Recombinant Human CD37 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala113-Asn240.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    Andere Bezeichnung
    CD37 (TSPAN26 Produkte)
    Synonyme
    Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
    Hintergrund
    CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
    Molekulargewicht
    41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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