PROC Protein (His tag)

Produktnummer ABIN7198701

Produktdetails

Target: PROC (Vitamin K-dependent protein C (PROC))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PROC Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PROC1/Protein C/PROC Protein (His Tag)

Sequenz: Met 1-Pro461

Produktmerkmale: A DNA sequence encoding the human PROC (P04070) (Met1-Pro461) was expressed with a C-terminal polyhistidine tag.

Reinheit: (79+20.5) % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PROC (Vitamin K-dependent protein C (PROC))

Andere Bezeichnung: PROC1 (PROC Produkte)

Synonyme: proc Protein, si:ch1073-188c16.3 Protein, zgc:63987 Protein, PROC Protein, APC Protein, PC Protein, PROC1 Protein, THPH3 Protein, THPH4 Protein, proc1 Protein, MGC64425 Protein, PA Protein, protein C, inactivator of coagulation factors Va and VIIIa Protein, protein C (inactivator of coagulation factors Va and VIIIa), a Protein, protein C (inactivator of coagulation factors Va and VIIIa) Protein, protein C, inactivator of coagulation factors Va and VIIIa S homeolog Protein, vitamin K-dependent protein C Protein, prosaposin Protein, protein C Protein, proline rich protein HaeIII subfamily 1 Protein, PROC Protein, proca Protein, proc.S Protein, proc Protein, CpipJ_CPIJ000393 Protein, CpipJ_CPIJ002754 Protein, CpipJ_CPIJ003717 Protein, CpipJ_CPIJ003718 Protein, CpipJ_CPIJ014440 Protein, CpipJ_CPIJ018032 Protein, CpipJ_CPIJ018737 Protein, PSAP Protein, Proc Protein, PRH1 Protein

Substanzklasse: Viral Protein

Hintergrund:

Background: CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.

Synonym: APC,PC,PROC,PROC1,THPH3,THPH4

Molekulargewicht: 51.5 kDa

UniProt: P04070