GALNT3 Protein (His tag)

Produktnummer ABIN7318920

Produktdetails

Target: GALNT3 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses GALNT3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GALNT3 Protein (His Tag)

Sequenz: Gln38-Asp633

Produktmerkmale: Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 3 is produced by our Mammalian expression system and the target gene encoding Gln38-Asp633 is expressed with a 6His tag at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: GALNT3 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3))

Andere Bezeichnung: GALNT3 (GALNT3 Produkte)

Synonyme: GalNAc-T3 Protein, HFTC Protein, HHS Protein, polypeptide N-acetylgalactosaminyltransferase 3 Protein, Galnt3 Protein, GALNT3 Protein

Hintergrund:

Background: Polypeptide N-acetylgalactosaminyltransferase 3(GALNT3) belongs to the glycosyltransferase 2 family and galNAc-T subfamily. It expressed in organs that contain secretory epithelial glands and it highly expressed in pancreas, skin, kidney and testis. There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding .This protein plays a major role in regulating phosphate levels within the body (phosphate homeostasis). Among its many functions, phosphate plays a critical role in the formation and growth of bones in childhood and helps maintain bone strength in adults.

Synonym: Polypeptide N-acetylgalactosaminyltransferase 3, Polypeptide GalNAc transferase 3, GalNAc-T3, pp-GaNTase 3, Protein-UDP acetylgalactosaminyltransferase 3, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3, HFTC, HHS

Molekulargewicht: 69.1 kDa

UniProt: Q14435