UBE2V2 Protein (His tag)

Produktnummer ABIN7319155

Produktdetails

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBE2V2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human UBE2V2/DDVIT1 Protein (His Tag)

Sequenz: Met 1-Asn145

Produktmerkmale: Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn145 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50mm HEPES,150 mM NaCl, pH 7.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Andere Bezeichnung: UBE2V2/DDVIT1 (UBE2V2 Produkte)

Synonyme: DDVIT1 Protein, DDVit-1 Protein, EDAF-1 Protein, EDPF-1 Protein, EDPF1 Protein, MMS2 Protein, UEV-2 Protein, UEV2 Protein, mms2 Protein, uev2 Protein, edpf1 Protein, uev-2 Protein, ddvit1 Protein, edaf-1 Protein, edpf-1 Protein, ddvit-1 Protein, 1110021H13Rik Protein, 4632410D19Rik Protein, 5730524P06Rik Protein, 6820402M05 Protein, AI848315 Protein, C81524 Protein, wu:fb18b11 Protein, wu:fb24d11 Protein, zgc:63717 Protein, UBE2V2 Protein, TMEM189-UBE2V1 Protein, ubiquitin conjugating enzyme E2 V2 Protein, ubiquitin-conjugating enzyme E2 variant 2 Protein, ubiquitin conjugating enzyme E2 V2 S homeolog Protein, Ubiquitin-conjugating enzyme E2 variant 2 Protein, UBE2V2 Protein, Ube2v2 Protein, ube2v2 Protein, ube2v2.S Protein, PTRG_00824 Protein, ub2v2 Protein, Tsp_08004 Protein

Hintergrund:

Background: Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Synonym: Ubiquitin-Conjugating Enzyme E2 Variant 2, DDVit 1, Enterocyte Differentiation-Associated Factor 1, EDAF-1, Enterocyte Differentiation-Promoting Factor 1, EDPF-1, MMS2 Homolog, Vitamin D3-Inducible Protein, UBE2V2, MMS2, UEV2

Molekulargewicht: 18.5 kDa

UniProt: Q15819

Pathways: Positive Regulation of Response to DNA Damage Stimulus