TNFRSF19 Protein (His tag)

Produktnummer ABIN7198467

Produktdetails

Target: TNFRSF19 (Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNFRSF19 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse TNFRSF19/TROY Protein (His Tag)

Sequenz: Met 1-Leu 170

Produktmerkmale: A DNA sequence encoding the extracellular domain (Met 1-Leu 170) of mouse TNFRSF19 (NP_001157627.1) was fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: TNFRSF19 (Tumor Necrosis Factor Receptor Superfamily, Member 19 (TNFRSF19))

Andere Bezeichnung: TNFRSF19/TROY (TNFRSF19 Produkte)

Synonyme: TNFRSF19 Protein, DKFZp468A0320 Protein, TAJ Protein, TAJ-alpha Protein, TRADE Protein, TROY Protein, AL023044 Protein, AW123854 Protein, TAJ-ALPHA Protein, Troy Protein, RGD1564996 Protein, TNF receptor superfamily member 19 Protein, tumor necrosis factor receptor superfamily, member 19 Protein, TNFRSF19 Protein, Tnfrsf19 Protein

Hintergrund:

Background: Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.

Synonym: AL023044,AW123854,TAJ,TAJ-ALPHA,TRADE,Troy

Molekulargewicht: 17 kDa

NCBI Accession: NP_001157627