TPSB2 Protein (His tag)

Produktnummer ABIN7319120

Produktdetails

Target: TPSB2 (Tryptase beta 2 (TPSB2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses TPSB2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Tryptase β-2/TPSB2 Protein (His Tag)

Sequenz: Ala19-Pro275

Produktmerkmale: Recombinant Human Tryptase beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: TPSB2 (Tryptase beta 2 (TPSB2))

Andere Bezeichnung: Tryptase beta-2/TPSB2 (TPSB2 Produkte)

Synonyme: TPS2 Protein, tryptaseB Protein, tryptaseC Protein, Mcpt6 Protein, tryptase beta 2 (gene/pseudogene) Protein, tryptase beta 2 Protein, TPSB2 Protein, Tpsb2 Protein

Hintergrund:

Background: Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

Synonym: Tryptase Beta-2, Tryptase-2, Tryptase II, TPSB2, TPS2

Molekulargewicht: 29.6 kDa

UniProt: P20231