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TMEM27 Protein (Fc Tag)

TMEM27 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7317264
  • Target Alle TMEM27 Proteine anzeigen
    TMEM27 (Transmembrane Protein 27 (TMEM27))
    Protein-Typ
    Recombinant
    Spezies
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Quelle
    • 8
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TMEM27 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human TMEM27 Protein (Fc Tag)
    Sequenz
    Met 1-Pro141
    Produktmerkmale
    A DNA sequence encoding the human TMEM27 (Q9HBJ8) (Met1-Pro141) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TMEM27 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    TMEM27 (Transmembrane Protein 27 (TMEM27))
    Andere Bezeichnung
    TMEM27 (TMEM27 Produkte)
    Synonyme
    NX17 Protein, nx-17 Protein, MGC68634 Protein, collectrin Protein, tmem27 Protein, NX-17 Protein, 0610008J07Rik Protein, Nx17 Protein, transmembrane protein 27 L homeolog Protein, si:dkey-194e6.1 Protein, transmembrane protein 27 Protein, tmem27.L Protein, si:dkey-194e6.1 Protein, TMEM27 Protein, tmem27 Protein, Tmem27 Protein
    Hintergrund

    Background: TMEM27 is a membrane protein. It has been proposed as a beta cell mass biomarker since it is cleaved and shed by pancreatic beta cells. Overexpression of TMEM27 leads to increased thymidine incorporation, whereas silencing of Tmem27 using RNAi results in a reduction of cell replication. Furthermore, transgenic mice with increased expression of Tmem27 in pancreatic beta cells exhibit increased beta cell mass. TMEM27 is also important for trafficking amino acid transporters to the apical brush border of proximal tubules.

    Synonym: NX-17,NX17

    Molekulargewicht
    41.4 kDa
    UniProt
    Q9HBJ8
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