TFAP2C Protein (His tag)

Produktnummer ABIN7317304

Produktdetails

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TFAP2C Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human TFAP2C/AP2-GAMMA Protein (His Tag)

Sequenz: Leu128-Val223

Produktmerkmale: A DNA sequence encoding the mature form of human TFAP2C (Q92754) (Leu128-Val223) was expressed with a polyhistide tag at the N-terminus.

Reinheit: > 98 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Andere Bezeichnung: TFAP2C/AP2-GAMMA (TFAP2C Produkte)

Synonyme: erf1 Protein, hap-2g Protein, tfa2pc Protein, tfap2g Protein, ap2-gamma Protein, TFAP2C Protein, AP2-gamma Protein, Tcfap2c Protein, AP2-GAMMA Protein, ERF1 Protein, TFAP2G Protein, hAP-2g Protein, wu:fb48g05 Protein, wu:fb49c04 Protein, zgc:92088 Protein, ap-2g Protein, tfap2gamma Protein, AA409384 Protein, AP2gamma Protein, Ap-2.2 Protein, Stra2 Protein, transcription factor AP-2 gamma Protein, putative transcription factor ap-2 gamma Protein, transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) Protein, transcription factor AP-2 gamma S homeolog Protein, transcription factor AP-2, gamma Protein, tfap2c Protein, TFAP2C Protein, Smp_157840 Protein, Tfap2c Protein, tfap2c.S Protein

Hintergrund:

Background: TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested for association to diseases (Breast Neoplasms, Carcinoma) and proposed to participate in processes (cell-cell signaling, male gonad development, regulation of transcription from RNA polymerase II promoter). Proteins are expected to have molecular functions (DNA binding, protein binding, protein dimerization activity, transcription factor activity) and to localize in various compartments (membrane, nucleus).

Synonym: AP2-GAMMA,ERF1,hAP-2g,TFAP2G

Molekulargewicht: 12.3 kDa

UniProt: Q92754

Pathways: Stem Cell Maintenance