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TLK1 Protein (GST tag,His tag)

TLK1 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7317054
  • Target Alle TLK1 Proteine anzeigen
    TLK1 (Tousled-Like Kinase 1 (TLK1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 5
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Aufreinigungstag / Konjugat
    Dieses TLK1 Protein ist gelabelt mit GST tag,His tag.
    Verwendungszweck
    Recombinant Human TLK1/PKU-beta Protein (His & GST Tag)(Active)
    Sequenz
    Met 1-Tyr 766
    Produktmerkmale
    A DNA sequence encoding the human TLK1 isoform 1 (Q9UKI8-1) (Met 1-Tyr 766) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
    Reinheit
    > 88 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    The specific activity was determined to be 1.6 nmol/min/mg using Histone H3 protein as substrate.
    Top Product
    Discover our top product TLK1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    TLK1 (Tousled-Like Kinase 1 (TLK1))
    Andere Bezeichnung
    TLK1/PKU-beta (TLK1 Produkte)
    Synonyme
    PKU-beta Protein, 4930545J15Rik Protein, fe11e12 Protein, si:dkey-251e16.4 Protein, tlk1 Protein, wu:fe11e12 Protein, TLK1 Protein, fb76h12 Protein, si:dkey-88m1.1 Protein, wu:fb76h12 Protein, DKFZp459L163 Protein, tousled like kinase 1 Protein, tousled-like kinase 1 Protein, tousled-like kinase 1b Protein, tousled like kinase 1 like Protein, serine/threonine-protein kinase TOUSLED Protein, tousled-like kinase 1a Protein, Serine/threonine-protein kinase tousled-like 1 Protein, TLK1 Protein, Tlk1 Protein, tlk1b Protein, TLK1L Protein, LOC542181 Protein, tlk1a Protein, tlk1 Protein, tlk-1 Protein
    Hintergrund

    Background: The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

    Synonym: KIAA0137,PKU-beta

    Molekulargewicht
    114 kDa
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