TXNL4A Protein (His tag)

Produktnummer ABIN7317379

Produktdetails

Target: TXNL4A (Thioredoxin-Like 4A (TXNL4A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TXNL4A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human DIM1/TXNL4A Protein (His Tag)

Sequenz: Met 1-Tyr 142

Produktmerkmale: A DNA sequence encoding the human TXNL4A (P83876) (Met 1-Tyr 142) was expressed, with a polyhistidine tag at the N-terminus.

Reinheit: > 94 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 150 mM NaCl, pH 8.0

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: TXNL4A (Thioredoxin-Like 4A (TXNL4A))

Andere Bezeichnung: DIM1/TXNL4A (TXNL4A Produkte)

Synonyme: Txnl4 Protein, TXNL4A Protein, txnl4a Protein, dim1 Protein, MGC85128 Protein, DIB1 Protein, DIM1 Protein, HsT161 Protein, SNRNP15 Protein, TXNL4 Protein, U5-15kD Protein, D18Wsu98e Protein, Dim1 Protein, ENSMUSG00000057130 Protein, U5-15kDa Protein, thioredoxin-like 4A Protein, thioredoxin like 4A Protein, thioredoxin like 4A S homeolog Protein, Txnl4a Protein, TXNL4A Protein, txnl4a Protein, LOC664328 Protein, txnl4a.S Protein

Hintergrund:

Background: DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. In spite of their biological and structural similarities, DIM1 and Dim2 proteins differ in many aspects. DIM1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. DIM1 interacts with HNRPF, HNRPH2, NEDD9/HEF1 and PQBP1/NPW38. It plays an essential role in pre-mRNA splicing.

Synonym: BMKS,DIB1,DIM1,SNRNP15,TXNL4,U5-15kD

Molekulargewicht: 18.6kDa

UniProt: P83876

Pathways: Ribonucleoprotein Complex Subunit Organization