ST6GAL1 Protein (His tag)

Produktnummer ABIN7319313

Produktdetails

Target: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses ST6GAL1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ST6GAL1 Protein (His Tag)

Sequenz: Lys27-Cys406

Produktmerkmale: Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Lys27-Cys406 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))

Andere Bezeichnung: ST6GAL1 (ST6GAL1 Produkte)

Synonyme: SIAT1 Protein, ST6GalI Protein, ST6N Protein, Siat1 Protein, siat1 Protein, zgc:136454 Protein, ST6GAL1 Protein, AW742324 Protein, St6Gal-I Protein, St6gal Protein, St6galI Protein, ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Protein, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 Protein, beta galactoside alpha 2,6 sialyltransferase 1 Protein, ST6GAL1 Protein, St6gal1 Protein, st6gal1 Protein

Hintergrund:

Background: The ST6GAL1 gene encodes β-Galactosamide α-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galβ1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.

Synonym: Beta-Galactoside Alpha-2,6-Sialyltransferase 1, Alpha 2,6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1

Molekulargewicht: 44.6 kDa

UniProt: P15907