SPESP1 Protein (His tag)

Produktnummer ABIN7319050

Produktdetails

Target: SPESP1 (Sperm Equatorial Segment Protein 1 (SPESP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SPESP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SPESP1 Protein (His Tag)

Sequenz: Tyr20-Tyr350

Produktmerkmale: Recombinant Human Sperm Equatorial Segment Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr20-Tyr350 is expressed with a 6His tag at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: SPESP1 (Sperm Equatorial Segment Protein 1 (SPESP1))

Andere Bezeichnung: SPESP1 (SPESP1 Produkte)

Synonyme: ESP Protein, SP-ESP Protein, 4921508E09Rik Protein, AI428149 Protein, RGD1563468 Protein, sperm equatorial segment protein 1 Protein, SPESP1 Protein, Spesp1 Protein

Hintergrund:

Background: Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis, it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and it contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.

Synonym: Sperm Equatorial Segment Protein 1, ESP, Equatorial Segment Protein, SP-ESP, Glycosylated 38 kDa Sperm Protein C-7/8, SPESP1

Molekulargewicht: 37.9 kDa

UniProt: Q6UW49