SPEG Protein (His tag)

Produktnummer ABIN7198099

Produktdetails

Target: SPEG (SPEG Complex Locus (SPEG))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SPEG Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SPEG/APEG-1 Protein (His Tag)

Sequenz: Met 1-Glu 113

Produktmerkmale: A DNA sequence encoding the human SPEG isoform 3 (Q15772-4) (Met 1-Glu 113) was fused with a polyhistidine tag at the C-terminus.

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as sterile PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: SPEG (SPEG Complex Locus (SPEG))

Andere Bezeichnung: SPEG/APEG-1 (SPEG Produkte)

Synonyme: apeg1 Protein, fc31c10 Protein, im:6912258 Protein, wu:fc31c10 Protein, APEG-1 Protein, APEG1 Protein, BPEG Protein, SPEGalpha Protein, SPEGbeta Protein, AW125581 Protein, Apeg1 Protein, D1Bwg1450e Protein, mKIAA1297 Protein, SPEG complex locus a Protein, SPEG complex locus Protein, spega Protein, SPEG Protein, Speg Protein

Hintergrund:

Background: Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein which belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expressed in the aorta. Isoform 3 of SPEG appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC. Isoform 3 of SPEG may have a role in regulating the growth and differentiation of arterial smooth muscle cells. Isoform 3 of SPEG is quickly down-regulated in response to vascular injury, when ASMC cells change from a quiescent to a proliferative phenotype.

Synonym: APEG-1;APEG1;BPEG;CNM5;SPEGalpha;SPEGbeta

Molekulargewicht: 14 kDa