SPINK4 Protein (His tag)

Produktnummer ABIN7197926

Produktdetails

Target: SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SPINK4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SPINK4 Protein (His Tag)

Sequenz: Met 1-Cys 86

Produktmerkmale: A DNA sequence encoding the human SPINK4 (NP_055286.1) (Met 1-Cys 86) was expressed, fused with a polyhistidine tag at the C-terminus.

Reinheit: > 97 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))

Andere Bezeichnung: SPINK4 (SPINK4 Produkte)

Synonyme: PEC-60 Protein, PEC60 Protein, MPGC60 Protein, serine peptidase inhibitor, Kazal type 4 Protein, SPINK4 Protein, Spink4 Protein

Hintergrund:

Background: Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-60 homolog and SPINK4, is a secreted protein which contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.

Synonym: Serine Protease Inhibitor Kazal-Type 4, Peptide PEC-60 Homolog, SPINK4,HEL136,MGC133107,PEC-60,PEC60

Molekulargewicht: 8 kDa

NCBI Accession: NP_055286