SCGB1A1 Protein (His tag)

Produktnummer ABIN7319415

Produktdetails

Target: SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SCGB1A1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Uteroglobin/SCGB1A1 Protein (His Tag)

Sequenz: Glu22-Asn91

Produktmerkmale: Recombinant Human Uteroglobin is produced by our Mammalian expression system and the target gene encoding Glu22-Asn91 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))

Andere Bezeichnung: Uteroglobin/SCGB1A1 (SCGB1A1 Produkte)

Synonyme: CC10 Protein, CC16 Protein, CCPBP Protein, CCSP Protein, UGB Protein, UP-1 Protein, UP1 Protein, UGL Protein, PCB-BP Protein, UG Protein, Utg Protein, PCBB Protein, Ugb Protein, SCGB1A1 Protein, secretoglobin family 1A member 1 Protein, secretoglobin, family 1A, member 1 (uteroglobin) Protein, urinary protein 2 Protein, SCGB1A1 Protein, Scgb1a1 Protein, Rup2 Protein

Hintergrund:

Background: Uteroglobin is a small, non-glycosylated secreted protein of the secretoglobin superfamily. It is produced by the non-ciliated, non-mucous secretory cells that predominate in lung bronchioles (Clara cells), and other non-ciliated epithelia that communicate with the external environment. Expression is induced by steroid hormones such as estrogen, and enhanced by the non-steroid hormone prolactin. Human Uteroglobin cDNA encodes a 21 amino acid (aa) signal sequence and a 70 aa mature protein. The mature protein forms a disulfide-linked head-to-tail homodimer of 16 kDa. This homodimer is thought to form a binding pocket that binds hydrophobic ligands such as phospholipids, progesterone and retinols. Binding of fibronectin to Uteroglobin in the kidney is thought to protect against nephropathy, while binding of the lipocalin-1 receptor has been reported to suppress cancer cell motility and invasion.

Synonym: Uteroglobin, Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, UP-1, UP1, Urine protein 1, SCGB1A1, CCSP, UGB

Molekulargewicht: 8.7 kDa

UniProt: P11684