S100A2 Protein

Produktnummer ABIN7319734

Produktdetails

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Verwendungszweck: Recombinant Human S100A2 Protein

Sequenz: Met1-Pro98

Produktmerkmale: Recombinant Human S100A2 is produced by our E.coli expression system and the target gene encoding Met1-Pro98 is expressed.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Andere Bezeichnung: S100A2 (S100A2 Produkte)

Synonyme: S100A2 Protein, CAN19 Protein, S100L Protein, CaN19 Protein, EG628324 Protein, S100 calcium binding protein A2 Protein, S100A2 Protein, S100a2 Protein

Hintergrund:

Background: The calcium-binding Protein S100-A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100-A2 was first detected in lung and kidney, and is mainly expressed in a subset of tissues and cells such as breast epithelia and liver. The S100A2 protein is a homodimer that undergoes a conformational change upon binding of calcium, and the active form functions in regulating cell proliferation and differentiation, gene transcription, and p53-dependent growth arrest and apoptosis. This protein is regarded as a putative tumor suppressor, and thus chromosomal rearrangements and reduced expression of S100A2 gene have been implicated in certain carcinomas.

Synonym: Protein S100-A2, CAN19, Protein S-100L, S100 calcium-binding protein A2, S100A2, S100L

Molekulargewicht: 11.2 kDa

UniProt: P29034

Pathways: S100 Proteine