RCN3 Protein (AA 1-324) (His tag)

Produktnummer ABIN7317231

Produktdetails

Target: RCN3 (Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-324

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RCN3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Reticulocalbin 3/RCN3 Protein (aa 1-324, His Tag)

Sequenz: Met 1-His324

Produktmerkmale: A DNA sequence encoding the human RCN3 (Q96D15) (Met1-His324) was expressed with a polyhistidine tag at the C-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: RCN3 (Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3))

Andere Bezeichnung: Reticulocalbin 3/RCN3 (RCN3 Produkte)

Synonyme: RLP49 Protein, 6030455P07Rik Protein, D530026G20Rik Protein, D7Ertd671e Protein, reticulocalbin 3 Protein, reticulocalbin 3, EF-hand calcium binding domain Protein, RCN3 Protein, Rcn3 Protein

Hintergrund:

Background: RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.

Synonym: Reticulocalbin-3, EF-Hand Calcium-Binding Protein RLP49, RCN3

Molekulargewicht: 36.2 kDa

UniProt: Q96D15