REG3A Protein (His tag)

Produktnummer ABIN7320383

Produktdetails

Target: REG3A (Regenerating Islet-Derived 3 alpha (REG3A))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses REG3A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse REG3A/HIP Protein (His Tag)

Sequenz: Met1-Gln175

Produktmerkmale: A DNA sequence encoding the extracellular domain (Met1-Gln175) of mouse REG3A (NP_035389.1) precursor was expressed with a C-terminal polyhistidine tag.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: REG3A (Regenerating Islet-Derived 3 alpha (REG3A))

Andere Bezeichnung: REG3A/HIP (REG3A Produkte)

Synonyme: HIP Protein, HIP/PAP Protein, INGAP Protein, PAP Protein, PAP-H Protein, PAP1 Protein, PBCGF Protein, REG-III Protein, REG3 Protein, AV063448 Protein, Pap2 Protein, PapII Protein, PTP Protein, REG3G Protein, regenerating family member 3 alpha Protein, regenerating islet-derived 3 alpha Protein, REG3A Protein, Reg3a Protein

Hintergrund:

Background: Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.

Synonym: AV063448,Rega3a

Molekulargewicht: 18 kDa

NCBI Accession: NP_035389