RAB11B Protein (His tag)

Produktnummer ABIN7317178

Produktdetails

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RAB11B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human RAB11B Protein (His Tag)

Sequenz: Gly2-Cys215

Produktmerkmale: A DNA sequence encoding the human RAB11B (ABQ59034.1) (Gly2-Cys215) was expressed with a polyhistidine tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))

Andere Bezeichnung: RAB11B (RAB11B Produkte)

Synonyme: zgc:92772 Protein, H-YPT3 Protein, A730055L17Rik Protein, rab11b Protein, wu:fb07g11 Protein, zgc:55760 Protein, RAB11B, member RAS oncogene family, b Protein, RAB11B, member RAS oncogene family Protein, RAB11B, member RAS oncogene family, a Protein, RAB11B, member RAS oncogene family, gene 1 S homeolog Protein, rab11bb Protein, RAB11B Protein, Rab11b Protein, rab11ba Protein, rab11b.1.S Protein

Hintergrund:

Background: The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization.

Synonym: H-YPT3

Molekulargewicht: 26.3 kDa

Pathways: Hormone Transport, Carbohydrate Homeostasis