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POMGNT1 Protein (His tag)

POMGNT1 Spezies: Human Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318922
  • Target Alle POMGNT1 Proteine anzeigen
    POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 2
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses POMGNT1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human POMGNT1 Protein (His Tag)
    Sequenz
    Leu59-Thr660
    Produktmerkmale
    Recombinant Human Protein O-Linked-Mannose beta-1 2-N-Acetylglucosaminyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Leu59-Thr660 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product POMGNT1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 8.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
    Andere Bezeichnung
    POMGNT1 (POMGNT1 Produkte)
    Synonyme
    POMGNT1 Protein, im:7151461 Protein, zgc:158130 Protein, 0610016I07Rik Protein, 4930467B06Rik Protein, GNTI.2 Protein, GnT I.2 Protein, LGMD2O Protein, MDDGA3 Protein, MDDGB3 Protein, MDDGC3 Protein, MEB Protein, MGAT1.2 Protein, gnT-I.2 Protein, protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Protein, protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) S homeolog Protein, protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase Protein, POMGNT1 Protein, pomgnt1.S Protein, pomgnt1 Protein, Pomgnt1 Protein
    Hintergrund

    Background: Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).

    Synonym: Protein O-Linked-Mannose Beta-1,2-N-Acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1,2-N-Acetylglucosaminyltransferase I.2,POMGNT1, MGAT1.2

    Molekulargewicht
    69.3 kDa
    UniProt
    Q8WZA1
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