PDIA3 Protein (His tag)

Produktnummer ABIN7318949

Produktdetails

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses PDIA3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ERP57/PDIA3 Protein (His Tag)

Sequenz: Ser25-Leu505

Produktmerkmale: Recombinant Human Protein Disulfide-Isomerase A3 is produced by our Mammalian expression system and the target gene encoding Ser25-Leu505 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: ERP57/PDIA3 (PDIA3 Produkte)

Synonyme: ER60 Protein, ERp57 Protein, ERp60 Protein, ERp61 Protein, GRP57 Protein, GRP58 Protein, HsT17083 Protein, P58 Protein, PI-PLC Protein, grp-58 Protein, 58kDa Protein, Erp Protein, Grp58 Protein, PDI Protein, PDI-Q2 Protein, PLC[a] Protein, Plca Protein, 1 Protein, 25D3-membrane-associated Protein, sb:cb825 Protein, erp57 Protein, grp58 Protein, pdia3 Protein, protein disulfide isomerase family A member 3 Protein, protein disulfide-isomerase A3 Protein, protein disulfide isomerase associated 3 Protein, protein disulfide isomerase family A, member 3 Protein, protein disulfide isomerase family A member 3 S homeolog Protein, PDIA3 Protein, Tsp_10062 Protein, Pdia3 Protein, pdia3 Protein, pdia3.S Protein

Hintergrund:

Background: PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

Synonym: PDIA3 protein,Protein disulfide-isomerase A3,58 kDa glucose-regulated protein,Disulfide isomerase ER-60,ER protein 57

Molekulargewicht: 55.3 kDa

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis