PRSS2 Protein (His tag)

Produktnummer ABIN7197544

Produktdetails

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PRSS2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Trypsin 2/PRSS2 Protein (His Tag)(Active)

Sequenz: Met 1-Asn 246

Produktmerkmale: A DNA sequence encoding the mouse PRSS2 (NP_033456.1) precursor (Met 1-Asn 246) was expressed, with a C-terminal polyhistidine tag.

Reinheit: > 92 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Anaspec, Catalog #27096). The specific activity is >1500 pmoles/min/μg.(Activation description: The proenzyme needs to be activated by enteropeptidase for an activated form)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.5

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Andere Bezeichnung: Trypsin 2/PRSS2 (PRSS2 Produkte)

Synonyme: Dvir\\GJ21501 Protein, Dvtry-2 Protein, GJ21501 Protein, Try2 Protein, dvir_GLEANR_6854 Protein, TRY8 Protein, TRYP Protein, Ta Protein, Tesp4 Protein, Ptryss2 Protein, TRY2 Protein, TRYP2 Protein, trypsin-2 Protein, Trypsin-2 Protein, protease, serine 2 Protein, protease, serine, 2 Protein, trypsin II Protein, CpipJ_CPIJ000771 Protein, CpipJ_CPIJ020109 Protein, Dvir\Try2 Protein, Prss2 Protein, PRSS2 Protein, trp-ii Protein

Hintergrund:

Background: Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein which belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary for the uptake of protein in the food. It is secreted by the pancreas in the form of inactive zymogen, trypsinogen and cleaved to its active form in the small intestine when the pancreas is stimulated by cholecystokinin through the common activation mechanism.

Synonym: Prss2;Ta;Tesp4;Try2;TRY8;TRYP

Molekulargewicht: 26.2 kDa

NCBI Accession: NP_033456