PDCD4 Protein (His tag)
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- Target Alle PDCD4 Proteine anzeigen
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PDCD4 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human PDCD4/H731 Protein (His Tag)
- Sequenz
- Lys212-Pro357
- Produktmerkmale
- Recombinant Human Programmed Cell Death Protein 4 is produced by our E.coli expression system and the target gene encoding Lys212-Pro357 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDCD4 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Andere Bezeichnung
- PDCD4/H731 (PDCD4 Produkte)
- Synonyme
- H731 Protein, D19Ucla1 Protein, Ma3 Protein, Tis Protein, Dug Protein, cb45 Protein, pdcd4 Protein, sb:cb45 Protein, wu:fc84b08 Protein, h731 Protein, MGC69337 Protein, PDCD4 Protein, wu:fa55g03 Protein, wu:fb08a11 Protein, wu:fe01a02 Protein, zgc:66311 Protein, programmed cell death 4 Protein, programmed cell death 4b Protein, programmed cell death 4 L homeolog Protein, programmed cell death 4 (neoplastic transformation inhibitor) Protein, programmed cell death 4a Protein, PDCD4 Protein, Pdcd4 Protein, pdcd4b Protein, pdcd4.L Protein, pdcd4 Protein, pdcd4a Protein
- Hintergrund
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Background: Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.
Synonym: Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731
- Molekulargewicht
- 17.0 kDa
- UniProt
- Q53EL6
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