PSG6 Protein (His tag)

Produktnummer ABIN7317194

Produktdetails

Target: PSG6 (Pregnancy Specific beta-1-Glycoprotein 6 (PSG6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses PSG6 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PSG6/PSG10 Protein (His Tag)

Sequenz: Met 1-His 424

Produktmerkmale: A DNA sequence encoding the human PSG6 (Met 1-His 424) (NP_001027020) was expressed, with a C-terminal polyhistidine tag.

Reinheit: > 87 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PSG6 (Pregnancy Specific beta-1-Glycoprotein 6 (PSG6))

Andere Bezeichnung: PSG6/PSG10 (PSG6 Produkte)

Synonyme: PSBG-10 Protein, PSBG-12 Protein, PSBG-6 Protein, PSG10 Protein, PSGGB Protein, PSG6 Protein, PSG3 Protein, pregnancy specific beta-1-glycoprotein 6 Protein, pregnancy-specific beta-1-glycoprotein 4 Protein, PSG6 Protein, LOC456082 Protein

Hintergrund:

Background: PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

Synonym: CGM3,PSBG-10,PSBG-12,PSBG-6,PSG10,PSG12,PSG6,PSGGB

Molekulargewicht: 45.2 kDa

NCBI Accession: NP_001027020