PLA2G12B Protein (His tag)

Produktnummer ABIN7320191

Produktdetails

Target: PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PLA2G12B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse PLA2G12B/PLA2G13 Protein (His Tag)

Sequenz: Met 1-Leu 195

Produktmerkmale: A DNA sequence encoding the mouse PLA2G12B (NP_076019.2) (Met 1-Leu 195) was expressed, with a C-terminal polyhistidine tag.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM NaAc, 100 mM NaCl, pH 5.0

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))

Andere Bezeichnung: PLA2G12B/PLA2G13 (PLA2G12B Produkte)

Synonyme: wu:fb26d02 Protein, wu:fb99g06 Protein, wu:fc91d12 Protein, zgc:111897 Protein, zgc:56487 Protein, zgc:77746 Protein, MGC79728 Protein, GXIIB Protein, GXIIIsPLA2 Protein, PLA2G13 Protein, 2010002E04Rik Protein, Pla2g13 Protein, hlb218 Protein, phospholipase A2, group XIIB Protein, phospholipase A2 group XIIB Protein, pla2g12b Protein, PLA2G12B Protein, Pla2g12b Protein

Hintergrund:

Background: Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein which belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strong expression in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Phospholipases A2 / PLA2 are commonly found in mammalian tissues as well as insect and snake venom. Venom from both snakes and insects is largely composed of melittin, which is a stimulant of Phospholipases A2 / PLA2. Due to the increased presence and activity of Phospholipases A2 / PLA2 resulting from a snake or insect bite, arachidonic acid is released from the phospholipid membrane disproportionately. As a result, inflammation and pain occur at the site.

Synonym: 2010002E04Rik;Fksg71;hlb218;Pla2g13

Molekulargewicht: 21 kDa

NCBI Accession: NP_076019