PDAP1 Protein (His tag)
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- Target Alle PDAP1 Proteine anzeigen
- PDAP1 (PDGFA Associated Protein 1 (PDAP1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PDAP1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human PDAP1/PAP Protein (His Tag)
- Sequenz
- Met 1-Lys181
- Produktmerkmale
- Recombinant Human PDGF-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys181 is expressed with a 6His tag at the N-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDAP1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 100 mM NaCl, 0.1 mM PMSF, 2 mM DTT, pH 8.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- PDAP1 (PDGFA Associated Protein 1 (PDAP1))
- Andere Bezeichnung
- PDAP1/PAP (PDAP1 Produkte)
- Synonyme
- pdap1 Protein, zgc:56213 Protein, HASPP28 Protein, PAP Protein, PAP1 Protein, Haspp28 Protein, pdgfa associated protein 1b Protein, 28 kDa heat- and acid-stable phosphoprotein Protein, PDGFA associated protein 1 Protein, pdap1b Protein, CpipJ_CPIJ013582 Protein, PDAP1 Protein, Pdap1 Protein
- Hintergrund
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Background: Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.
Synonym: 28 kDa Heat- and Acid-Stable Phosphoprotein, PDGF-Associated Protein, PAP, PDGFA-Associated Protein 1, PAP1, PDAP1, HASPP28
- Molekulargewicht
- 22.8 kDa
- UniProt
- Q13442
- Pathways
- Platelet-derived growth Factor Receptor Signaling
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