PTH1R Protein (His tag)
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- Target Alle PTH1R Proteine anzeigen
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses PTH1R Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human PTH1R Protein (Gly49, His Tag)
- Sequenz
- Tyr23-Met 189
- Produktmerkmale
- Recombinant Human Parathyroid hormone 1 receptor is produced by our Mammalian expression system and the target gene encoding Tyr23-Met189 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PTH1R Protein
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Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) protein (GST tag)
PTH1R Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-188) protein (His tag)Crystallography grade PTH1R Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 464-591) protein (His tag)Crystallography grade PTH1R Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-591) protein (rho-1D4 tag)Crystallography grade PTH1R Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- Andere Bezeichnung
- PTH1R (PTH1R Produkte)
- Synonyme
- PFE Protein, PTHR Protein, PTHR1 Protein, PPR Protein, Pthr Protein, Pthr1 Protein, pthr1 Protein, zPTH1R Protein, PTHrel Protein, PTH1 Protein, PTH Protein, parathyroid hormone 1 receptor Protein, parathyroid hormone 1 receptor a Protein, PTH1R Protein, Pth1r Protein, pth1ra Protein
- Hintergrund
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Background: Parathyroid hormone 1 receptor(PTH1R) is a multi-pass membrane protein. The protein is expressed in high levels in bone and kidney and regulates calcium ionhomeostasis through activation of adenylate cyclase and phospholipase C. In bone, it is expressed on the surface of osteoblasts. When the receptor is activated through PTH binding, osteoblasts express RANKL (Receptor Activator of Nuclear Factor kB Ligand), which binds to RANK (Receptor Activator of Nuclear Factor kB) on osteoclasts. This turns on osteoclasts to ultimately increase the resorption rate.
Synonym: Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH/PTHrP type I receptor,PTH/PTHr receptor,Parathyroid hormone 1 receptor,PTH1 receptor,PTH1R
- Molekulargewicht
- 20.2 kDa
- UniProt
- Q0VGD7
- Pathways
- Regulation of Carbohydrate Metabolic Process
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