NAALADL1 Protein (His tag)

Produktnummer ABIN7320106

Produktdetails

Target: NAALADL1 (N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NAALADL1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse NAALADL1 Protein (His Tag)

Sequenz: Pro 29-Leu 745

Produktmerkmale: A DNA sequence encoding the secreted form of mouse NAALADL1 (Q7M758) (Pro 29-Leu 745) was fused with a polyhistidine tag at the N-terminus.

Reinheit: > 97 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: NAALADL1 (N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1))

Andere Bezeichnung: NAALADL1 (NAALADL1 Produkte)

Synonyme: I100 Protein, NAALADASEL Protein, Gm964 Protein, Naaladasel Protein, N-acetylated alpha-linked acidic dipeptidase like 1 Protein, N-acetylated alpha-linked acidic dipeptidase-like 1 Protein, NAALADL1 Protein, Naaladl1 Protein

Hintergrund:

Background: N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.

Synonym: Gm964,Naaladasel

Molekulargewicht: 80 kDa

UniProt: Q7M758