MBIP Protein (His tag)

Produktnummer ABIN7318766

Produktdetails

Target: MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MBIP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human MBIP Protein (His Tag)

Sequenz: Met 1-Pro344

Produktmerkmale: Recombinant Human MAP3K12-Binding Inhibitory Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Pro344 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))

Andere Bezeichnung: MBIP (MBIP Produkte)

Synonyme: 4933408E06Rik Protein, MAP3K12 binding inhibitory protein 1 Protein, Mbip Protein, mbip Protein, MBIP Protein

Hintergrund:

Background: MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It's function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.

Synonym: MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP

Molekulargewicht: 42.5 kDa

UniProt: Q9NS73