CDH15 Protein (Fc Tag)

Produktnummer ABIN7321152

Produktdetails

Target: CDH15 (M-Cadherin (CDH15))

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CDH15 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Rat Cadherin-15/CDH15 Protein (Fc Tag)

Sequenz: Met1-Gly602

Produktmerkmale: A DNA sequence encoding the rat CDH15 (Q75NI5) (Met1-Gly602) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Reinheit: > 92 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CDH15 (M-Cadherin (CDH15))

Andere Bezeichnung: Cadherin-15/CDH15 (CDH15 Produkte)

Synonyme: AI323380 Protein, Cdh14 Protein, Mcad Protein, CDH14 Protein, CDH3 Protein, CDHM Protein, MCAD Protein, MRD3 Protein, cadherin 15 Protein, Cdh15 Protein, CDH15 Protein

Hintergrund:

Background: Cadherin-15, also known as CDH15, is a member of the cadherin superfamily. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-15 contains 5 cadherin domains. It is expressed in some normal epithelial tissues and in some carcinoma cell lines. Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM), also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.

Synonym: CDH15

Molekulargewicht: 90.6 kDa

UniProt: Q75NI5