LSAMP Protein (Fc Tag)

Produktnummer ABIN7317408

Produktdetails

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LSAMP Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human LSAMP Protein (Fc Tag)(Active)

Sequenz: Met 1-Asn 315

Produktmerkmale: A DNA sequence encoding the human LSAMP (Q13449) (Met 1-Asn 315), without the pro peptide, was was fused with the Fc region of human IgG1 at the C-terminus.

Reinheit: > 97 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized recombinant human OPCML-His at 10 μg/mL can bind recombinant human LSAMP-Fc with a linear range of 31.25-250 ng/ml.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Andere Bezeichnung: LSAMP (LSAMP Produkte)

Synonyme: chLAMP Protein, IGLON3 Protein, LAMP Protein, 5430428I19 Protein, AW046674 Protein, B130007O04Rik Protein, D930023J12Rik Protein, Lam Protein, Lamp Protein, limbic system-associated membrane protein Protein, LSAMP Protein, Lsamp Protein

Hintergrund:

Background: The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68- kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions, also learning and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule, serving as a guidance cue for specific patterns of connectivity, which underlies the normal development of the limbic system. In animal studies there have been found that rats with increased level of anxiety had 1.6-fold higher expression of LsAMP gene in the periaqueductal gray compared to rats with low level of anxiety, indicating a possible role of LsAMP in the regulation of anxiety.

Synonym: FLJ34254,FLJ35396,FLJ37216,FLJ54658,IGLON3,LAMP

Molekulargewicht: 59 kDa

UniProt: Q13449