IL1RAPL2 Protein (His tag)

Produktnummer ABIN7196312

Produktdetails

Target: IL1RAPL2 (Interleukin 1 Receptor Accessory Protein-Like 2 (IL1RAPL2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL1RAPL2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human IL-1R9/IL1RAPL2 Protein (His Tag)(Active)

Sequenz: Met 1-Glu 356

Produktmerkmale: A DNA sequence encoding the extracellular domain (Met 1-Glu 356) of human IL1R9 (NP_059112.1) was expressed, with a C-terminal polyhistidine tag.

Reinheit: > 98 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to bind biotinylated human IL1α in functional ELISA.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IL1RAPL2 (Interleukin 1 Receptor Accessory Protein-Like 2 (IL1RAPL2))

Andere Bezeichnung: IL-1R9/IL1RAPL2 (IL1RAPL2 Produkte)

Synonyme: il18r Protein, il1r9 Protein, il-1r9 Protein, tigirr-1 Protein, MGC146607 Protein, il1rapl-2 Protein, IL-1R9 Protein, IL1R9 Protein, IL1RAPL-2 Protein, TIGIRR-1 Protein, RGD1561761 Protein, interleukin 1 receptor accessory protein-like 2 Protein, interleukin 1 receptor accessory protein like 2 Protein, X-linked interleukin-1 receptor accessory protein-like 2 Protein, ilrapl2 Protein, IL1RAPL2 Protein, LOC492045 Protein, il1rapl2 Protein, LOC100403193 Protein, Il1rapl2 Protein

Hintergrund:

Background: X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptor are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

Synonym: IL-1R9,IL1R9,IL1RAPL-2,TIGIRR-1

Molekulargewicht: 40.7 kDa

NCBI Accession: NP_059112