ITLN1/Omentin Protein (His tag)

Produktnummer ABIN7318846

Produktdetails

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ITLN1/Omentin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Intelectin-1/ITLN1 Protein (His Tag)

Sequenz: Thr19-Ser298

Produktmerkmale: Recombinant Human Intelectin-1 is produced by our E.coli expression system and the target gene encoding Thr19-Ser298 is expressed with a 6His tag at the N-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris,100 mMNaCl, 5 mM GSH, 0.5 mM GSSG, pH 8.0 .

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Andere Bezeichnung: Intelectin-1/ITLN1 (ITLN1 Produkte)

Synonyme: IntL Protein, Itln Protein, Itln2 Protein, Itln5 Protein, Itlna Protein, Lfr Protein, HL-1 Protein, HL1 Protein, INTL Protein, ITLN Protein, LFR Protein, hIntL Protein, omentin Protein, LfR Protein, Xeel Protein, hl-1 Protein, hl1 Protein, intl Protein, itln Protein, itln1 Protein, lfr Protein, xeel Protein, INTL1 Protein, zgc:153267 Protein, intelectin 1 (galactofuranose binding) Protein, intelectin 1 Protein, intelectin 1 L homeolog Protein, Itln1 Protein, ITLN1 Protein, itln1.L Protein, itln1 Protein

Hintergrund:

Background: Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.

Synonym: Intelectin-1, ITLN-1, Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, INTL, ITLN, LFR

Molekulargewicht: 32.7 kDa

UniProt: Q8WWA0