HBA1 Protein (His tag)

Produktnummer ABIN7318569

Produktdetails

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HBA1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human HBA1 Protein (His Tag)

Sequenz: Met 1-Arg142

Produktmerkmale: Recombinant Human Hemoglobin subunit alpha is produced by our E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Andere Bezeichnung: HBA1 (HBA1 Produkte)

Synonyme: HBA1 Protein, HBAM Protein, Hba-a1 Protein, Hba-a2 Protein, cd31 Protein, hba-a Protein, hba2 Protein, HBH Protein, HBA2 Protein, alpha globin Protein, CD31 Protein, Hba Protein, Hba1 Protein, Hbat1 Protein, AA1 Protein, dZ118J2.2 Protein, HBAI Protein, HBAII Protein, hemoglobin, alpha 1 Protein, hemoglobin subunit alpha 1 Protein, hemoglobin subunit alpha 1 S homeolog Protein, hemoglobin subunit alpha 2 Protein, hemoglobin, alpha 2 Protein, hemoglobin subunit alpha-like Protein, hemoglobin alpha, adult chain 1 Protein, alpha-hemoglobin Protein, hemoglobin subunit alpha Protein, hemoglobin, alpha adult 1 Protein, hemoglobin subunit alpha-2-like Protein, HBA Protein, Hba1 Protein, hba1 Protein, hba1.S Protein, HBA1 Protein, HBA2 Protein, LOC100737768 Protein, Hba-a1 Protein, LOC100472013 Protein, LOC100087130 Protein, hbaa1 Protein, LOC102168959 Protein

Hintergrund:

Background: Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2, H+, Cl?, and 2,3-DPG (2,3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans, which mediates the transport of oxygen and carbon dioxide in the blood. In recent years, Hb α and β chains have been found co-expressed in alveolar cells, mesangial cells of the kidney, retinal ganglion cells, hepatocytes and neurons. Endothelial and peripheral catecholaminergic cells express exclusively the α chain, while macrophages present the β chain only.

Synonym: Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1,HBH, HBA-T3

Molekulargewicht: 16.7 kDa

UniProt: P69905