GSTM2 Protein (GST tag,His tag)

Produktnummer ABIN7317428

Produktdetails

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GSTM2 Protein ist gelabelt mit GST tag,His tag.

Verwendungszweck: Recombinant Human GSTM2/GST4 Protein (His Tag)

Sequenz: Met 1-Lys 218

Produktmerkmale: A DNA sequence encoding the native human GSTM2 (P28161) (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus.

Reinheit: > 97 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 150 mM NaCl, 10 mM CaCl2, 0.05 % Brig-35, pH 7.5

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Andere Bezeichnung: GSTM2/GST4 (GSTM2 Produkte)

Synonyme: GSTA4 Protein, GST4 Protein, GSTM Protein, GSTM2-2 Protein, GTHMUS Protein, Gstb-2 Protein, Gstb2 Protein, GSTIV Protein, glutathione S-transferase mu 2 Protein, glutathione S-transferase mu 2 (muscle) Protein, glutathione S-transferase Mu 2 Protein, glutathione S-transferase, mu 2 Protein, glutathione S-transferase 2 Protein, Glutathione S-transferase 4 Protein, Gstm2 Protein, GSTM2 Protein, LOC100732167 Protein, gst2 Protein, gst-4 Protein

Hintergrund:

Background: Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

Synonym: GST4;GSTM;GSTM2-2;GTHMUS

Molekulargewicht: 27.2 kDa

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity