GBA3 Protein (His tag)

Produktnummer ABIN7195930

Produktdetails

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses GBA3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GBA3/CBGL1 Protein (His Tag)(Active)

Sequenz: Met 1-Leu 469

Produktmerkmale: A DNA sequence encoding the human GBA3 (NP_066024.1) (Met 1-Leu 469) was fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to hydrolyze 4-methylumbelliferyl-β-D glucopyranoside. The specific activity is >1,500 pmoles/min/μg.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: GBA3/CBGL1 (GBA3 Produkte)

Synonyme: im:6912508 Protein, CBG Protein, CBGL1 Protein, GLUC Protein, KLRP Protein, glucosylceramidase beta 3 Protein, glucosidase, beta, acid 3 (gene/pseudogene) Protein, glucosidase, beta, acid 3 (cytosolic) Protein, cytosolic beta-glucosidase Protein, glucosylceramidase beta 3 (gene/pseudogene) Protein, Gba3 Protein, gba3 Protein, GBA3 Protein, LOC100344458 Protein

Hintergrund:

Background: "Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to the glycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.

Synonym: CBG;CBGL1;GBA3;GLUC;KLrP;MGC104276;MGC126878

Molekulargewicht: 55 kDa

NCBI Accession: NP_066024