LGALS7 Protein (GST tag)

Produktnummer ABIN7317435

Produktdetails

Target: LGALS7 (Galectin 7 (LGALS7))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LGALS7 Protein ist gelabelt mit GST tag.

Verwendungszweck: Recombinant Human Galectin-7/LGALS7 Protein (GST Tag)(Active)

Sequenz: Ser 2-Phe 136

Produktmerkmale: A DNA sequence encoding the human LGALS7 (P47929) (Ser 2-Phe 136) was fused with the GST tag at the N-terminus.

Reinheit: > 92 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Measured by its ability to agglutinate human red blood cells.The ED50 for this effect is typically 0.01-0.05 μg/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.5

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LGALS7 (Galectin 7 (LGALS7))

Andere Bezeichnung: Galectin-7/LGALS7 (LGALS7 Produkte)

Synonyme: GAL7 Protein, LGALS7A Protein, Galectin-7 Protein, Pig1 Protein, LGALS7 Protein, galectin-7 Protein, galectin 7 Protein, lectin, galactose binding, soluble 7 Protein, galectin-7 Protein, LGALS7 Protein, Lgals7 Protein, LOC101112249 Protein

Hintergrund:

Background: LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members in this family. Galectins share similarities in the CRD (the carbohydrate recognition domain). They are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide, galectins can also be stimulated to secretion by non-classical pathways or alternatively targeted to the nucleus. Galectins are implicated in modulating cell-cell and cell-matrix interactions. LGALS7 contains 1 galectin domain and is mainly expressed in stratified squamous epithelium. Galectin-7 could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. LGALS7 is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Synonym: Galectin-7, Gal-7, HKL-14, PI7, p53-Induced Gene 1 Protein, LGALS7, PIG1, LGALS7B

Molekulargewicht: 41.8 kDa

UniProt: P47929