GPR114 Protein (Fc Tag)

Produktnummer ABIN7317740

Produktdetails

Target: GPR114 (G Protein-Coupled Receptor 114 (GPR114))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GPR114 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human GPR114 Protein (Fc Tag)

Sequenz: Met 1-Gly184

Produktmerkmale: A DNA sequence encoding the human GPR114 (Q8IZF4) (Met1-Gly184) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Reinheit: > 94 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: GPR114 (G Protein-Coupled Receptor 114 (GPR114))

Andere Bezeichnung: GPR114 (GPR114 Produkte)

Synonyme: PGR27 Protein, Gm1109 Protein, adhesion G protein-coupled receptor G5 Protein, ADGRG5 Protein, Adgrg5 Protein

Hintergrund:

Background: GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane domains, three extracellular loops, three intracellular loops, an amino-terminal extracellular domain and an intracellular carboxyl terminus. It is thought that light acts as the activating stimulus of a G-protein-coupled receptor (GPCR). GPCRs are expected to have molecular function (G-protein coupled receptor activity) and to localize in various compartments (endoplasmic reticulum membrane, plasma membrane, integral to membrane). Family B of the GPCRs is a small but structurally and functionally diverse group of proteins that includes receptors for polypeptide hormones, molecules thought to mediate intercellular interactions at the plasma membrane and a group of Drosophila proteins that regulate stress responses and longevity. GPR114 contains 1 GPS domain. GPR114 gene has been proposed to participate in processes (G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway).

Synonym: GPR114,PGR27

Molekulargewicht: 45.6 kDa

UniProt: Q8IZF4