FLRT2 Protein (His tag)

Produktnummer ABIN7319323

Produktdetails

Target: FLRT2 (Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses FLRT2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human FLRT2 Protein (His Tag)

Sequenz: Cys36-Ser539

Produktmerkmale: Recombinant Human Fibronectin Leucine Rich Transmembrane Protein 2 is produced by our Mammalian expression system and the target gene encoding Cys36-Ser539 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FLRT2 (Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2))

Andere Bezeichnung: FLRT2 (FLRT2 Produkte)

Synonyme: fibronectin leucine rich transmembrane protein 2 S homeolog Protein, fibronectin leucine rich transmembrane protein 2 Protein, flrt2.S Protein, flrt2 Protein, FLRT2 Protein, Flrt2 Protein

Hintergrund:

Background: Fibronectin Leucine Rich Transmembrane protein 2 (FLRT2) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell cell association. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting its involvement in the FGF signalling pathway.

Synonym: Leucine-Rich Repeat Transmembrane Protein FLRT2, Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2, FLRT2, KIAA0405

Molekulargewicht: 57.3 kDa

UniProt: O43155