FGF17 Protein (His tag)

Produktnummer ABIN7320525

Produktdetails

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FGF17 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse FGF-17 Protein (His Tag)(Active)

Sequenz: Thr23-Thr216

Produktmerkmale: Recombinant Mouse Fibroblast Growth Factor 17 is produced by our E.coli expression system and the target gene encoding Thr23-Thr216 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by SDS-PAGE

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells. The ED50 for this effect is 1.26 ug/ml, in the presence of 10 μg/mL heparin.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl,EDTA,DTT, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Andere Bezeichnung: FGF-17 (FGF17 Produkte)

Synonyme: FGF17 Protein, FGF-13 Protein, HH20 Protein, fgf17b Protein, zgc:101759 Protein, fibroblast growth factor 17 Protein, FGF17 Protein, Fgf17 Protein, fgf17 Protein

Hintergrund:

Background: FGF-17 is a member of the fibroblast growth factor (FGF) family. FGFs share 30 70 % amino acid (aa) identity in a conserved, approximately 120 amino acid core domain. FGFs play multiple roles in biological functions, including angiogenesis, mitogenesis, cell differentiation and wound repair. FGF17 plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also expressed in hindgut, parts of the developing skeleton, tail bud, major arteries, and heart. In many of these areas, it is expressed along with FGF-8, but slightly later. It is required for normal brain development.

Synonym: Fibroblast growth factor 17, FGF-17,fgf17

Molekulargewicht: 23.7 kDa

UniProt: P63075

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung