FABP3 Protein (His tag)

Produktnummer ABIN7319280

Produktdetails

Target: FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FABP3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human FABP3 Protein (His Tag)

Sequenz: Val2-Ala133

Produktmerkmale: Recombinant Human Fatty Acid-Binding Protein 3 is produced by our E.coli expression system and the target gene encoding Val2-Ala133 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 6.5.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))

Andere Bezeichnung: FABP3 (FABP3 Produkte)

Synonyme: Fabph-1 Protein, Fabph-4 Protein, Fabph1 Protein, Fabph4 Protein, H-FABP Protein, Mdgi Protein, FABP11 Protein, M-FABP Protein, MDGI Protein, O-FABP Protein, FABP Protein, FABP-3 Protein, fabp3 Protein, fatty acid binding protein 3 Protein, fatty acid binding protein 3, muscle and heart Protein, FABP3 Protein, Fabp3 Protein, fabp3 Protein

Hintergrund:

Background: Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. The FABP3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. FABP3 is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of onset of pain.

Synonym: Fatty Acid-Binding Protein Heart, Fatty Acid-Binding Protein 3, Heart-Type Fatty Acid-Binding Protein, H-FABP, Mammary-Derived Growth Inhibitor, MDGIMuscle Fatty Acid-Binding Protein, M-FABP, FABP3, FABP11, MDGI,H-FABP,O-FABP

Molekulargewicht: 17.0 kDa

UniProt: P05413

Pathways: Monocarboxylic Acid Catabolic Process