FAM20B Protein (Fc Tag)

Produktnummer ABIN7317190

Produktdetails

Target: FAM20B (Family with Sequence Similarity 20, Member B (FAM20B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses FAM20B Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human FAM20B/Gxk1 Protein (Fc Tag)

Sequenz: Ser31-Leu409

Produktmerkmale: A DNA sequence encoding the human FAM20B (NP_055679.1)(Ser31-Leu409) was expressed with the fused Fc region of human IgG1 at the N-terminus.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FAM20B (Family with Sequence Similarity 20, Member B (FAM20B))

Andere Bezeichnung: FAM20B/Gxk1 (FAM20B Produkte)

Synonyme: gxk1 Protein, C530043G21Rik Protein, mKIAA0475 Protein, FAM20B, glycosaminoglycan xylosylkinase Protein, family with sequence similarity 20, member B Protein, FAM20B Protein, Fam20b Protein

Hintergrund:

Background: PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

Synonym: gxk1

Molekulargewicht: 71.4 kDa

NCBI Accession: NP_055679