FAM171B Protein (His tag)

Produktnummer ABIN7195640

Produktdetails

Target: FAM171B (Family with Sequence Similarity 171, Member B (FAM171B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses FAM171B Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human FAM171B/KIAA1946 Protein (His Tag)

Sequenz: Met 1-Thr355

Produktmerkmale: A DNA sequence encoding the human FAM171B (AAH60872.1) (Met1-Thr355) was expressed with a C-terminal polyhistidine tag.

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FAM171B (Family with Sequence Similarity 171, Member B (FAM171B))

Andere Bezeichnung: FAM171B/KIAA1946 (FAM171B Produkte)

Synonyme: KIAA1946 Protein, D430039N05Rik Protein, family with sequence similarity 171 member B Protein, family with sequence similarity 171, member B Protein, FAM171B Protein, Fam171b Protein

Hintergrund:

Background: RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution, high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of RAMP3 protein, CRLR functions as an adrenomedullin receptor.

Synonym: KIAA1946

Molekulargewicht: 37.5 kDa