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ECM1 Protein (His tag)

ECM1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 88 % as determined by SDS-PAGE Active
Produktnummer ABIN7320312
  • Target Alle ECM1 Proteine anzeigen
    ECM1 (Extracellular Matrix Protein 1 (ECM1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 3
    • 1
    • 1
    Maus
    Quelle
    • 5
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ECM1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Mouse ECM1 Protein (His Tag)(Active)
    Sequenz
    Met 1-Glu 559
    Produktmerkmale
    A DNA sequence encoding the mouse ECM1 isoform 1 (Q61508-1) (Met 1-Glu 559) was expressed, fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 88 % as determined by SDS-PAGE
    Endotoxin-Niveau
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind human MMP-9 in a functional ELISA.
    Top Product
    Discover our top product ECM1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    ECM1 (Extracellular Matrix Protein 1 (ECM1))
    Andere Bezeichnung
    ECM1 (ECM1 Produkte)
    Synonyme
    URBWD Protein, ECM Protein, EMILIN4 Protein, GPIa* Protein, MMRN Protein, AI663821 Protein, p85 Protein, extracellular matrix protein 1 Protein, multimerin 1 Protein, ECM1 Protein, MMRN1 Protein, Ecm1 Protein
    Hintergrund

    Background: Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling. 

    Synonym: AI663821;p85

    Molekulargewicht
    62.5 kDa
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