EIF2C3 Protein (His tag)

Produktnummer ABIN7195623

Produktdetails

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses EIF2C3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human AGO3/Argonaute 3/EIF2C3 Protein (His Tag)

Sequenz: Met 1-Ala 860

Produktmerkmale: A DNA sequence encoding the human EIF2C3 (Q9H9G7-1) (Met 1-Ala 860) was expressed, with a polyhistidine tag at the N-terminus.

Reinheit: > 88 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Andere Bezeichnung: AGO3/Argonaute 3/EIF2C3 (EIF2C3 Produkte)

Synonyme: EIF2C3 Protein, Eif2c3 Protein, Argonaute3 Protein, ago3 Protein, eif2c3 Protein, eif2c3b Protein, si:dkey-3n22.3 Protein, AW048688 Protein, C130014L07Rik Protein, ARGONAUTE 3 Protein, T19E23.8 Protein, T19E23_8 Protein, argonaute 3, RISC catalytic component Protein, argonaute RISC catalytic component 3b Protein, argonaute RISC catalytic subunit 3 Protein, argonaute RISC catalytic component 3 Protein, ARGONAUTE 3 Protein, AGO3 Protein, Ago3 Protein, ago3b Protein

Hintergrund:

Background: Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.

Synonym: EIF2C3

Molekulargewicht: 99.6 kDa

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung