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EDNRB Protein (Fc Tag)

EDNRB Spezies: Human Wirt: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7317189
  • Target Alle EDNRB Proteine anzeigen
    EDNRB (Endothelin Receptor Type B (EDNRB))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 2
    • 1
    Human
    Quelle
    • 3
    • 3
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses EDNRB Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human EDNRB/Endothelin B Receptor Protein (Fc Tag)
    Sequenz
    Met 1-Lys101
    Produktmerkmale
    A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with the Fc region of mouse IgG1 at the C-terminus.
    Reinheit
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product EDNRB Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    EDNRB (Endothelin Receptor Type B (EDNRB))
    Andere Bezeichnung
    EDNRB/Endothelin B Receptor (EDNRB Produkte)
    Synonyme
    ABCDS Protein, ET-B Protein, ET-BR Protein, ETB Protein, ETBR Protein, ETRB Protein, HSCR Protein, HSCR2 Protein, WS4A Protein, Ednra Protein, Etb Protein, ETR-b Protein, ETb Protein, Sox10m1 Protein, EDNRB Protein, abcds Protein, etb Protein, etrb Protein, hscr Protein, hscr2 Protein, endothelin receptor type B Protein, EDNRB Protein, Ednrb Protein, ednrb Protein
    Hintergrund

    Background: The hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors.

    Synonym: ABCDS,ET-B,ET-BR,ETB,ETBR,ETRB,HSCR,HSCR2,WS4A

    Molekulargewicht
    34.4 kDa
    NCBI Accession
    NP_000106
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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